Abortion Should Be Illegal Essay -- Persuasive Essay

Around the globe numerous ladies are getting premature births lawfully and illicitly. I think accepting premature births ought to be illegal, except for assault and interbreeding. Ending the life of an unborn individual isn't just pitiless yet off-base. The choice of taking another individuals life ought not lie in our grasp. In each general public whether it was lawful or lawful, premature births were utilized to control ripeness. In the United States it was polished legitimately until around 1880, by then most states had restricted it but to spare a lady's life. It was broadly polished through the whole time frame it was unlawful. In the 1890’s there were a gauge of 2,000,000 premature births for each year and, one to 2,000,000 every year during the 1920’s-30’s. Regardless of whether a lady could get a fetus removal depended on her monetary circumstance, race, and where she lived. Ladies with cash could leave the nation and find expensive specialists yet, helpless ladies who had no cash to leave and get one would preform self premature births. Either embeddings weaving needles or coat holders into the uterus and vagina, douching with perilous arrangements, for example, lye, or gulping solid medications and synthetic concoctions. A few hundred thousand ladies were treated for wellbei ng intricacies because of bungled, unsanitary, or self-instigated premature births. The laws forbidding premature births negatively affected women’s lives and wellbeing. Researchers assessed that roughly 5,000 lady had kicked the bucket in the U.S due to perilous premature births. Overall unintended, confused, and undesirable pregnancies are looked by all ladies in each nation and all societies. Some 20-30 million lawful premature births are preformed every year, and another 10-20 million that are preformed wrongfully. All around a gauge of 46 million premature births happen every y... ... minors look for parental assent or that a parent is informed in cutting edge of a minor having a premature birth. Starting at 2015, 35 states require that there is a type of parental inclusion with a minor accepting a premature birth. 22 states just require parental assent, eleven states just require parental notice, and just two states require parental assent and warning. There are obligatory periods that the lady needing to get a premature birth must get explicit data about the pregnancy and options first. Works Cited http://www.ourbodiesourselves.org/book/excerpt.asp?id=27 http://www.ourbodiesourselves.org/book/companion.asp?id=20&compID=40 http://www.emedicinehealth.com/premature birth/page2_em.htm http://www.friesian.com/abortion.htm http://www.abortionno.org/Resources/fastfacts.html http://health.nytimes.com/wellbeing/guides/medical procedure/premature birth/overview.html

Genetic Engineering Ethics Essay Sample

Hereditary Engineering Ethics Essay Sample Hereditary Engineering Ethics Essay Hereditary designing is the mix among natural and building applications that the populace doesn't perceive up right up 'til the present time. This is on the grounds that it is a calling that doesn't show their procedure in general society because of the issue of profound quality and moral statute. In any case, most organizations use hereditary building as an approach to adjust the food source to get gainful. These are organizations who are occupied with the creation of food items to gracefully the developing number of customers with transitory things. Hereditary designing is viewed as significant as a result of the usefulness and presence help to continue the endurance of living beings, for example, people and creatures. The act of hereditary building is broadly applied to assembling plants where they coordinate the utilization of innovation with natural life. You may not know that the food that you expend every day is made utilizing hereditary building applications. One model is moment nourishments that are pressed in plastic, box, or jars that are normally accessible in markets or supermarkets in your general vicinity. Handled meats are likewise considered hereditarily designed in light of the fact that it utilized various experimentation applications by researchers and specialists to improve the nature of taste just as its impact on the body. The explanation for is that organizations need to forestall any hazard for wellbeing for all buyers who need to attempt their item. Cheap food organizations are substantial clients of hereditary designing in light of the fact that most of their food is hereditarily built by their creation offices. One announced situation is when there is one cheap food chain that is creating chickens with three sets of legs to guarantee the developing interest of the populace around the globe. Hereditary building has been under analysis because of their act of adjusting living beings. The primary pundit is the congregation, which dismisses the act of hereditarily changed living beings since it damages the standards of ethical quality. Change of life form for food has been addressed in light of the fact that it depicts the validity of the organization for advancing items that are normally developed. For this situation, the estimation of altered creature that is sold for food or things that help physical movement is some of the time denied by preservationist government establishments. All creatures ought not be falsely developed in light of the fact that it obliterates the substance of advancing an item that is comprised of counterfeit blends. Once in a while, organizations who are engaged with hereditary designing practice to their items are called for investigation procedures by the administrators of a specific nation to decide whether there are laws that were abused for c hanging items with counterfeit materials. In the current period, hereditary designing may not be an agreeable subject for the overall population since it produces banter. This is on the grounds that moderate gatherings dismiss the idea about altering the regular components of our condition. Be that as it may, with the rising populace and the developing requirement for space, hereditary building assists with continuing humanity’s endurance. This is on the grounds that hereditary designing may be the response for the developing shortage of assets that are liable for draining the food gracefully around the globe. Immature nations can't give food to their locale because of the absence of regular asset to take care of its populace. With the presence of hereditary designing, it can help spare our condition by permitting an extra wellspring of food flexibly to forestall appetite and starvation that impacts the wellbeing and life span of the populace (Pollack, 2015). Hereditary building is applied in the pharmacological business wherein clinical specialists are expecting to discover a fix to a specific ailment. Inoculation is an away from of hereditary building since it esteems the hugeness of finding another answer for improve the personal satisfaction for each patient. When there are new prescriptions that are currently being prepared, therapeutically tried, and affirmed, it turns into a product in the market so individuals can have an entrance to the recently figured medicine to improve their social insurance status. In medication, the making of adjusted structure through the production of new medication plans to forestall the spread of a malady that is viewed as destructive and conceivably dangerous to the populace. In spite of the fact that it is tested by the warriors of traditionalism, hereditary qualities despite everything keep on fusing logical investigations and experimentation to profit the enthusiasm of the populace. So as to comprehend the mechanics of hereditary building, it is critical to become familiar with the capacity of this specific application. The explanation for is to situate general society with respect to the advantages of this application that can give a legitimate usefulness later on. Hereditary designing is a result of human’s basic dynamic procedure to guarantee that the wellbeing of general society is constantly guaranteed. The general objective of hereditary building is the maintainability of each person to carry on with a more drawn out life. Regardless of whether there are difficulties that are worried by intrigue gatherings, hereditary building despite everything demonstrates that there is more gainful effect that it delivered as opposed to taking a chance with the lives of general society. In the event that there are infringement dedicated by organizations utilizing hereditary building to their customers or intrigue gatherings, at that point the neighborhood governm ent unit can capture the circumstance. Reference Pollack, Andrew (2015). Genetically Engineered Salmon Approved for Consumption. The New York Times.

International Business and Sustainable Development †Free Samples

Question: Disk about the International Business and Sustainable Development. Answer: Presentation In the cutting edge world, supportable business improvement is a significant factor for most business. Without appropriate maintainability in business, supervisors can't keep up the trust of the individuals. As per Holden, Linnerud Banister (2017), the expansion in the focal point of supportable advancement is on the grounds that chiefs need to comprehend the ways by which the nearby and local condition can be ensured. The report gives a point by point examination of the approaches to keep up maintainability by utilizing the idea of green structure. The report features the idea and the procedure received by chiefs so as to apply green structure in the zones of business. The significance of LEED affirmation and the impact of green structure on the lives of the individuals are dissected in this report. The report reveals insight into the appropriation of green structure by Beirut that adds to the development of green structures for keeping up maintainability in the business. As per Van Tulder, Verbeke Strange (2014), green structure is a procedure of building structures and procedures that help in keeping up the earth in a practical way. The arranging of green structure is done at an underlying phase of developing a structure. The development of green structures is asset proficient and helps in the best possible upkeep and improvement of a structure. It helps in deciding the existence pattern of a structure beginning at the phase of planning the structure, developing and keeping up the structure. As expressed by Griggs et al., (2013) the perfect development of green structure means ways that can help in protecting the common habitat. It can help in developing structures that help in keeping up the reason for keeping up an appropriate domain. Be that as it may, so as to accomplish this, participation and backing of the constructors and the planners is required. The planning of green structure extends and gives supplements to the structure of old style str uctures in the locales of business. In such manner, it tends to be said that the appropriation and development of the green structure have been embraced by Beirut in a powerful way. Beirut is an organization in France that spends significant time in structuring green structures. The organization intends to remove the advantages of green structure. A portion of the advantages that can be received with the ramifications of green structure incorporate decrease of waste and contamination from the earth. This can help in stopping the debasement of the earth and realize changes in the lives of the individuals. In such manner, Wheeler Beatley (2014) expressed that the idea of green housetop could achieve significant changes in the lives of the individuals. Green housetops can achieve the productive utilization of water, vitality and other applicable assets. These assets realize the advancement of supportability among the individuals and ensure the wellbeing and way of life of the people. Beirut has likewise figured out how to make a business for trading green items and administrations in the market. Along these lines, green structure has achieved numerous advantages th at have fundamentally influenced the development of manageability in the nation. In such manner, a procedure should be kept up that features the centrality of the idea. Procedure of green structure As expressed by Pearce, Barbier Markandya (2013) green structure requires a methodical procedure that helps in the advancement of manageability among the individuals. The procedure should be basic with the goal that individuals can receive the procedure successfully. In the light of this, it very well may be said that the sparing of vitality is a significant part of guaranteeing maintainability. It has been seen that comprehensively, enormous structures channel the most extreme measure of vitality, power and water utilization. This records for 18% of the complete vitality utilization in an area. Henceforth, it is critical to build up a procedure that prompts the preservation of these energies. The selection of sustainable hotspots for a residential reason can be expressed as a route by which green structure procedure can be applied. While executing the idea of green structure it is important to remember that the dividers and windows should be designed with green plants (Profile et al ., 2016). This can help in the best possible dissemination of oxygen in the structures and advance the significance of greenery among the individuals. This procedure can likewise help in building up a feasible domain in the structures. The green housetop can help in making a greenery climate for the people. It can likewise be a technique for expanding the business as a reception of green housetop can help in delivering leafy foods that can be sold in the market for an impressive benefit. This is another procedure that can be embraced by the structures empowering the idea of green structure in the districts. Thus, it tends to be said that the way toward embracing green structure can be both straightforward and savvy. For this situation, it very well may be said that Beirut receives this procedure in a powerful way and actualizes ways by which the manageability can be kept up. The adequacy where the organization spares vitality can help in expanding the vitality sources on the planet. In any case, in spite of the protection of vitality and other regular assets, the upkeep of green housetop requires abundance utilization of water. The capacity of water helps in tending to the issue and guarantees that the target of ke eping up manageability remains (Kolk, 2016). Warming reason Sun powered warming can be considered as the change of daylight so as to warm a structure and keep it hurt throughout the winter season. It can likewise be utilized to warm water or sun powered warm gatherer. Kibert (2016) expressed that different models of sunlight based warming are accessible that help in keeping up the necessary warmth in the structures relying on the temperature. The sun based warmers are additionally formed relying on the measure of warmth required in the structure and the plan of the structure. The vitality from the sun is utilized so as to save the sustainable wellsprings of vitality that exists on the planet. The immediate ingestion of vitality helps in effectively in a successful way. Aside from this, the sun powered board can likewise be utilized to give daylight to the plants in the housetop garden. This can help in the best possible creation of the consumables and guarantee that the market estimation of the consumables increments. Zuo Zhao (2014) saw that the sunlight based warmth is moved legitimately to the inside of the structure in the wake of having been put away in the reflection boards. In any case, a reinforcement framework is constantly required so as to control the disappointment of the framework. The warming reason used to keep up maintainability in the structures in Beirut is the sunlight based warming. This is on the grounds that the utilization of vitality from the sun can help in keeping up the non-inexhaustible assets and lessen contamination (Robertson, 2017). The utilization of light amassing mirror helps in catching the vitality and work freely utilizing electric gas radiators. This clears route for the viable utilization of vitality in the structures. The absence of room in the sun based board can be countered by the utilization of an assistant reinforcement framework that gives a warming procedure to warming the framework. Beirut utilizes fluid frameworks with the incorporation of capacity frameworks that help in brilliant warming. The utilization of fluid and air framework for warming can help in enhancing constrained framework that prompts the warming of air. This gives adequate dissemination of warmth in the structures with less utilization of vitality. In such m anner, the cooling framework utilized for bringing down temperatures during summer seasons can likewise be utilized to store vitality adequately. Cooling reason As per Eichholtz, Kok Quigley (2013), the utilization of normal ventilation can help in keeping the rooms cool and breezy. This can likewise help in appropriate course of air. The utilization of regular ventilation can help in controlling the air quality inside. The regular ventilation process helps in diminishing indoor contaminations, gives warm solace and guarantees that stickiness doesn't stay in the structures. The utilization of normal ventilation can help in the free flow of air around the structure. It weakens the nature of air ensuring that the destructive components don't hamper the development and soundness of the lives of the individuals. Harmsen, Hackmann Bos (2014) expressed that the utilization of normal ventilation decreases the reliance of machines that are utilized to give cooling. In this procedure, it helps in saving vitality and creates maintainability in the structures. Aside from this, the structuring of normal ventilation can lessen the expense of development of the structure by limiting the utilization of climate control systems and roof fans. On account of Beirut, the organization supports the utilization of normal ventilation in the structures so as to spare vitality utilization. This causes the structures to give a ceaseless gracefully of natural air and decrease toxins inside. The harmony among mugginess and temperature can be kept up at such a level, that it gives solace to the individuals dwelling in the structures. Another significant bit of leeway that regular ventilation gives is the way that it gives a simple break course if there should arise an occurrence of crisis (Wei, Ramalho Mandin, 2015). This is significant in light of the fact that mishaps may happen without earlier notification and can make serious issues the individuals. Beirut centers around planning such ventilation due to the point it has on decreasing the unsafe segments that exist noticeable all around. The air-borne illnesses can be decreased if the correct dissemination of air happens in the rooms. In this way, the utilization of regular ventila tion can help in setting up an appropriate harmony between the course of air and decrease of contaminants in the structure. In any case, so as to execute these methods, it is fundamental that the constructors guarantee that the LEED rating of the frameworks is adequate for the safe designi

How to Choose the Right Brand for Your E-commerce Business

Today, online shoppers have more choice & power than ever. Customer acquisition depends on you having a strong brand that resonates with your target audience. To get there, you need to be consistent, authentic, and fully aware of who you're talking to. Related: How to build a brand as an e-commerce business Getting this messaging right is a big challenge, but it's not impossible. By researching your audience and your niche, you can discover which kind of brand is right for you. Consider the following advice as you strive to make the right branding choices for your e-commerce business. Know your customers' values Learning your customers' values means building a relationship with them that goes deeper than just producer/consumer. When people recognize and trust your brand, it's because they see their own values reflected in it. One of the easiest ways to learn about your customers' values is simply to ask them. You could do some informal research on social media (or your blog) by covering certain topics and testing the engagement. Or, you could be even more scientific by conducting surveys and focus groups to learn more about the audience you're pursuing. After you've done this research, look back at your company. What do you already do that's aligned with the values of your customers? These are the messages that will ring out the loudest. When you can back up what you say with what you do, people will trust you and be drawn to your brand. [Click to tweet ] Begin by looking for the values you already share with your target audience, then find ways to embody the others. Know yourself The competition out there is endless, and the best way for you to stay afloat is to give customers something different to latch on to. This can be the products you sell, but if you combine this with a strong brand, you strengthen the connection you've already made with the customer. How do you uncover these strengths and differences? Start by developing your brand identity and brand personality, because these determine how you'll communicate with your target audience. These two dimensions exist to humanize your company. As social beings, people want to feel like they're buying from real people, especially when buying from an e-commerce business. It's a risk to purchase online, and they want to feel like they can trust you to do the right thing. By giving your brand an identity and personality, you're helping to create the image of a person inside the minds of shoppers. When they have a person in mind, they'll be more receptive to your brand messages. Beyond that, brand identity and personality serve different functions. A brand identity explains who and what your company is. It's your name, logo, colors, slogans... all the elements that identify your brand. As an e-commerce business, your identity will likely resemble a salesperson—you sell products people want or need. Your personality is more than that. It's how you sell. How do you present yourself? How do you talk? Do you care about certain issues? What do you believe? What do you not believe? These are things people connect to, and they'll develop stronger feelings about your brand when they know what these are. To choose the right brand for your company, you need a clear idea of who you are as a company. Consider writing down a mission statement, a vision, and a list of core values. This will crystallize the things your brand stands for, and as a result, your brand messaging will be more authentic and resonate better with your target audience. Know your story For as much as things have changed in the world, people still love a good story. Whether it's the story of a hero, an underdog, or simply the shared challenges and pleasures of the human experience, a good story moves people's hearts and minds. Every brand out there has a story—every one. The challenge is to share that story in a way that's authentic and relatable. It might take some time to discover the best way to communicate your story to your target audience. Start by zeroing in on your company's purpose, or more specifically, the problem you solve. Let's consider an example. Say you manage an e-commerce brand that sells eco-friendly furniture and clothing. What's your story? In short, you provide people with comfort and security in an environmentally friendly way. But there's something larger going on: climate change and the movement to address it. Your role in this global story is to meet people's basic needs at a significantly lower cost to the environment. Your brand creates better harmony between humans and the earth, and people who care about the planet will want to help your cause. In this example, your story represents and exemplifies your brand's values. Positioning your brand as an environmental activist, or as a lover and defender of nature, will help you connect with your target audience. This powerful brand image comes from digging into the story, bringing to light what it really is. L.L. Bean is a good real-life example of this. It started with a man designing his own pair of boots to make it easier and more enjoyable to walk around outside. But the larger story is about humanity's love of nature. Through this narrative lens, you can easily recognize L.L. Bean's brand. This is no coincidence. Of course, your history might not be as deep as L.L. Bean's, but it's still meaningful. Take some time to find the best way to communicate your story, and it will clarify and reinforce your brand in the eyes of your customers. Key takeaway For your e-commerce brand to stay successful, it needs to be authentic. When you're laying out your brand strategy, choose values and messaging that you and your customers truly believe in. By staying true to yourself and focusing on what you share with your audience, the right brand will emerge on its own. It might be challenging, but it shouldn't feel forced, and the results will definitely be worth it. Learn more about building & managing an online brand in our free ebook about brand management in the cloud.

Global Business International Business Concepts ...

ESSAY International Business Concepts Theories This paper references two recent newspaper articles, which focus on the rise of online retail in Australia and the decision of global retail giants to enter the Australian marketplace respectively. The paper aims to identify and discuss the implications for the Australian government, Australian businesses, particularly within the retail sector, as well as implications for international businesses which have been highlighted through these articles. This paper recognizes globalization as the most applicable and influential international business concept relevant to the changes within the Australian retail landscape. The paper also realizes theories related to differences in culture in†¦show more content†¦Furthermore, Australian based multinational companies, such as retail giants ranging from Westfield to David Jones have been forced to launch e-commerce sites in order to maintain a market share and a competitive advantage with international sites. The recent rapid expansion of global fast-fashion giants into the Australian marketplace has had a similar impact on the Australian fashion-retail industry that the increase in online shopping has, putting Australian retailers and small business under immense pressure and stress to remain in a position to compete with these global retailers. The article â€Å"Local retailers feel the heat from International invasion† published in The Sydney Morning Herald on November 26, 2013 highlights the ways in which ‘fast-fashion’ retailers have revolutionized how Australian consumers shop with big-name internationals establishing a presence within the Australian retail landscape . The article acknowledges that the catalyst for the International expansion of the majority of these retail giants has in fact been the internet. The expansion of retail giants into the Australian marketplace hasShow MoreRelatedCase Study on Asos Essay3981 Words   |  16 PagesUniversity of the Arts, London Tara Premnath A Case Study On The Globalisation And Strategic Reign Of ASOS Subject: Retail Branding and identity Abstract This report analysis the strategic branding policies of the online retailer ASOS and comprehends its position in the global market. It evaluates the standardisation and adaptation techniques ASOS employed to become the no.1 online retailer in the world. The company vigilantly practicesRead MoreStarbucks in China4917 Words   |  20 Pagesdollars in fiscal year of 2011, which rose 31.7% over the fiscal year of 2010. This Company is considered as a great business, which grows rapidly in past two decades. To illustrate this, in 1987 Howard Shultz and David Olsen bought Starbucks Company, and then five year later, it expanded from 6 shops to 165 retail outlets in Pacific Northwest. In 2001, Starbucks has more than 7,500 retail stores (Harrison et al. 2005). 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Therefore, collaboration among organisations that possess complementaryRead MoreStandardisation and Adaptation Within International Marketing Context24708 Words   |  99 PagesTHE UNIVERSITY OF HULL Integration of Standardisation and Adaptation Marketing Mix Strategy Reference to Shiseido Company in UK and China Being a Dissertation submitted in partial fulfilment of the requirements for the Degree of Master of Business Administration (General) in the University of Hull by Ai Jun Hou , BA (Honours) (April 20, 2001) Acknowledgement This dissertation reflects the contribution and insights of many people. I shall take the opportunity to thank the followingRead MoreEmerging Cities Of The Arab Emirates3204 Words   |  13 PagesArab Emirates is a very wealthy country due to their global position in the export of oil. Within this country is home of two prestigious cities in the development of becoming international hubs within the business and social world. 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The Helmet Law And Public Health Implications Of The Bill

In 2013, motorcycle helmet use in Michigan dropped to a record low approaching 73%, falling from 98% compliance just years earlier (â€Å"smarter-usa.org†). This drop can be attributed to the 2012 bill passed by Governor Rick Snyder, which declares certain qualified motorcyclists exempt from the previous mandatory compliance law (â€Å"smarter-usa.org†). The repercussions of this bill including effects on long term state supported medical care, organ donation, and increased insurance premiums pose a major public health issue (Satkoske, 2013). While motorcyclists claim their right to individual freedom of choice, the opposition expresses the concern that riding without a helmet is not only dangerous for riders, but also for the state of Michigan. This paper examines Michigan’s controversial optional helmet law, assessing arguments in favor of and against the bill. The need for state government involvement and the public health implications of the bill will also be discussed. Ultimately, the optional helmet law grants personal liberty, but also has created many arguments over the implications on public health. The State of Michigan motorcycle helmet law passed in 2012 as an amendment to Act 300, which mandated all motorcyclists wear an approved helmet while operating their vehicle (Johnson, n.d.). The amendment specifies that if a rider is 21 years old, carries 20,000 dollars in first-party medical benefits, and has had motorcycle endorsement for at least two years or passed anShow MoreRelatedThe Human Tissue Act 2008 Essay2256 Words   |  10 PagesBackground Currently in New Zealand the major law regarding the donation of organs is the Human Tissue Act 2008 introduced by the then labour government’s Minister of Health David Cunliffe. 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The National Hockey League began allowing sponsors to line along the interior walls of the ice rinks in the early 1980s. This, combined with new rules mandating players to wear helmets (though some were grandfathered), arguably gave the NHL a different look in the 1980s than compared with the 1970s. [edit] NFL While the now-defunct NFL Europe allowed liberal use of sponsors with the teams uniforms, the main National FootballRead MoreProduct Placement10682 Words   |  43 Pagesassociation football leagues eventually allowed sponsors of the uniforms. The National Hockey League began allowing sponsors to line along the interior walls of the ice rinks in the early 1980s. This, combined with new rules mandating players to wear helmets (though some were grandfathered), arguably gave the NHL a different look in the 1980s than compared with the 1970s. 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In 1992 Professor Hartley wrote Business Ethics: Violations of the Public Trust. Business Ethics Mistakes and Successes was published in 2005. He is listed in Who’s Who in America, and Who’s Who in the World. vii This page intentionally left blank CONTENTS Preface About the Author Chapter 1 Introduction

Tachypnoea Reduced Of Oxygen Saturation †Myassignmenthelp.Com

Question: Discuss About The Tachypnoea Reduced Of Oxygen Saturation? Answer: Introducation According to the case study, Mrs. Brown was presented with the clinical manifestations that included severe dyspnoea, tachypnoea, reduced level of oxygen saturation, hypertension, and tachycardia among other symptoms. Additionally bilateral basal crackles were detected on auscultation of lungs. Ultimately a diagnosis of acute exacerbation of chronic left-sided heart failure was arrived at by virtue of performing an electrocardiogram test that revealed presence of atrial fibrillation. Under the light of these manifestations, the pathogenesis of the disease related to left-sided heart failure may be explained. Empirical findings have suggested that systolic dysfunction may be attributed as the main etiologic factor that leads to left-sided heart failure. Systolic dysfunction refers to decreased ability to eject blood that in turn may be related to impaired contractility of the ventricles either due to fibrosis or destruction or abnormal functioning of the myocytes. Heightened resistanc e to flow also culminates in increased afterload which may lead to systolic dysfunction. All these factors account for causing the overstretching if the ventricles particularly the left ventricle that subsequently leads to decrease in myocardial contractility because of systolic dysfunction that has been identified as the predominant factor for heart failure. Diastolic dysfunction may also partially contribute for the onset of heart failure. Diastolic dysfunction arises because of impaired ventricular relaxation and impaired ventricular filing as a result of increased stiffness of the ventricular wall. For left-sided heart failure, impaired ventricular contractility may lead to conditions that encompass transient myocardial ischemia or myocardial infarction. Moreover mitral or aortic regurgitation might lead to chronic volume overload (Rosenkranz et al., 2015). Dilated cardiomyopathy is another characteristic feature of left-sided heart failure that in turn may be attributed to impa ired ventricular contractility because of systolic dysfunction of the heart. Systemic hypertension of uncontrolled type together with aortic stenosis also occurs in case of left-sided heart failure because of increased afterload. Apart from these systemic factors, the pathogenesis of left-sided heart failure is often linked to the deleterious consequences pertinent to the compensatory mechanisms that are responsible for maintaining the homeostasis inside the body. Continuous sympathetic activation, accentuated heart rate, increased circulating volume and preload in conjunction with increased total peripheral resistance and chronic elevation of angiotensin II enzyme and aldosterone hormone lead to the causation of left-sided heart failure due to combinatorial effects. In this connection, the two important symptoms related to the diagnosis of the disease in the patient that were manifested may be discussed for understanding their underlying mechanisms. Appearance of symptom related to shortness of breath might have occurred due to increased pulmonary oncotic pressure due to left-sided regurgitation is capable of extravasation of fluid into the pulmonary interstitium that in turn is reflected on decreased pulmonary compliance in addition to increased airway resistance. Further, the presence of bilateral basal crackles on pulmonary auscultation may be explained. Hydrostatic forces are found to be greatest at the lung bases whereby prior to inspiration, interstitial edema caused closure of small airways before opening them again. Higher lung regions represent crackles due to worsening pulmonary edema (Dupuis Guazzi, 2015). Considering the situation specific to Mrs. Brown, evidence based nursing strategies must be implemented to manage her condition and preventing further deterioration of her health status. The low level of oxygen saturation and increased respiratory rate is particularly alarming for the patient as these vital signs suggest the deteriorating health condition. Thus, supplemental oxygen therapy may be ensued for the patient to ensure no further exacerbation of the pulmonary congestion and hypoxic situation. Administration of adequate oxygen will ensure sufficient saturation for the patient. Adequate ventilation may be ensured through the utilization of nasal cannula for oxygen therapy thereby mitigating the sensation related to suffocation that might arise because of use of oxygen mask. However, precautions must be followed to avoid the risk of emphysema and hyperinflation of the lungs (Miguel-Montanes et al., 2015). Further her heart rate was found to be increased, deviating much beyond the normal limit. Therefore, efforts must be taken so that the cardiovascular functioning may be maintained at a satisfactory level. Hence, under the guidance and supervision of the attending physician, pharmacologic medications such as that of Digoxine may be administered. Digoxine is a digitalis that accounts for improving the contraction and rhythmicity of the heart through enhancing the myocardial contractility and cardiac output. Therapeutic effects of this drug cause the reduction in the pace of the heart rate that leads to stabilization of the heart rhythms (Ambrosy et al., 2014). However, the nurse must observe for any contraindications and any adverse outcomes must be promptly reported to the concerned physician. Mechanism of action of drugs and relation to underlying pathogenesis of acute exacerbation of chronic left-sided heart failure: IV furosemide: It is a diuretic that has been indicated for treating edema due to heart failure, hypertension and other pathological conditions related to renal disorders and hepatic impairment. It acts by inhibiting the reabsorption of sodium and chloride from the Loop of Henle of the kidney nephron ad distal renal tubules and cause increased renal excretion of water, sodium, chloride, magnesium, calcium and potassium. Thus the therapeutic effects are exerted through dieresis and consequent mobilization of excess fluid thereby reducing edema and pleural effusions alongside decreasing the blood pressure. Hence management of the left-sided heart failure is done by this drug (davisplus.fadavis.com., 2017). sublingual glyceryl trinitrate: It is considered as an antianginal that has been found to be beneficial in both acute as well as prophylactic management of angina pectoris besides acting as an adjunct therapy to treatment of heart failure. Dilation of coronary arteries and improvement of collateral flow to ischemic regions is acted upon by this drug through increasing the coronary blood flow. Further, it causes reduction of left ventricular end-diastolic pressure as well as left ventricular end-diastolic volume thereby acconting fir diminution of the myocardial oxygen consumption. Thus, the therapeutic effects on the treatment of left-sided heart failure by means of reliving the symptoms and prevention of heart attack are exerted by this drug. Reduction of blood pressure and increase of cardiac output is brought about by this drug that acts to alleviate the symptoms in case of left-sided heart failure (davisplus.fadavis.com., 2017). Nursing implications in treatment of patient with acute exacerbation of chronic left-sided heart failure: IV furosemide: Assessment of fluid status apart from monitoring of daily weight, intake and output ratios apart from location of edema, skin turgor, lung sounds and mucous membranes must be noted. At the time of administration as well as before that phase, monitoring of blood pressure must be conducted apart from assessing the falls risks in the elderly patients and subsequent implementation of fall prevention strategies. Any adverse reactions must be brought to the notice of the physician for prompt intervention (davisplus.fadavis.com., 2017). sublingual glyceryl trinitrate: Evaluation must be carried out with respect to the location, intensity, duration, and precipitating factors contributing to the patients angina pain. Continuous monitoring of the vital parameters through ECG must be done alongside evaluation of the additional hemodynamic parameters. Any notable contraindication must be immediately reported to the physician in charge (davisplus.fadavis.com., 2017). References Ambrosy, A. P., Butler, J., Ahmed, A., Vaduganathan, M., van Veldhuisen, D. J., Colucci, W. S., Gheorghiade, M. (2014). The use of digoxin in patients with worsening chronic heart failure: reconsidering an old drug to reduce hospital admissions.Journal of the American College of Cardiology,63(18), 1823-1832. Dupuis, J., Guazzi, M. (2015). Pathophysiology and clinical relevance of pulmonary remodelling in pulmonary hypertension due to left heart diseases.Canadian Journal of Cardiology,31(4), 416-429. Furosemide. (2017).davisplus.fadavis.com. Retrieved 12 August 2017, from https://davisplus.fadavis.com/3976/meddeck/pdf/furosemide.pdf Miguel-Montanes, R., Hajage, D., Messika, J., Bertrand, F., Gaudry, S., Rafat, C., ... Dreyfuss, D. (2015). Use of high-flow nasal cannula oxygen therapy to prevent desaturation during tracheal intubation of intensive care patients with mild-to-moderate hypoxemia.Critical care medicine,43(3), 574-583. Nitroglycerin. (2017).davisplus.fadavis.com. Retrieved 12 August 2017, from https://davisplus.fadavis.com/3976/meddeck/pdf/nitroglycerin.pdf Rosenkranz, S., Gibbs, J. S. R., Wachter, R., De Marco, T., Vonk-Noordegraaf, A., Vachiry, J. L. (2015). Left ventricular heart failure and pulmonary hypertension.European heart journal,37(12), 942-954.